The protective effect of infliximab against carbon tetrachloride-induced acute lung injury

Kurt A., Tumkaya L., Yuce S., Turut H., Cure M. C., Sehitoglu I., ...Daha Fazla

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.19, sa.6, ss.685-691, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 6
  • Basım Tarihi: 2016
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.685-691
  • Anahtar Kelimeler: Carbon tetrachloride, Infliximab, Nitric oxide, Pulmonary toxicity, Oxidative stress, CCL4-INDUCED OXIDATIVE STRESS, INDUCED LIVER-INJURY, RHIZOME EXTRACT, RATS, TOXICITY, ALPHA, AMELIORATION, FIBROSIS, DAMAGES, KIDNEY
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 induced lung injury.